Faecalibacterium prausnitzii and human intestinal health. - Université Pierre et Marie Curie Accéder directement au contenu
Article Dans Une Revue Current Opinion in Microbiology Année : 2013

Faecalibacterium prausnitzii and human intestinal health.

S. Miquel
O. Rossi
  • Fonction : Auteur
Lg Bermúdez-Humarán
  • Fonction : Auteur
Jm Chatel
  • Fonction : Auteur
M. Thomas
  • Fonction : Auteur
Jm Wells
  • Fonction : Auteur
P. Langella
  • Fonction : Auteur

Résumé

Faecalibacterium prausnitzii is the most abundant bacterium in the human intestinal microbiota of healthy adults, representing more than 5% of the total bacterial population. Over the past five years, an increasing number of studies have clearly described the importance of this highly metabolically active commensal bacterium as a component of the healthy human microbiota. Changes in the abundance of F. prausnitzii have been linked to dysbiosis in several human disorders. Administration of F. prausnitzii strain A2-165 and its culture supernatant have been shown to protect against 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in mice. Here, we discuss the role of F. prausnitzii in balancing immunity in the intestine and the mechanisms involved.

Domaines

Chimie organique

Dates et versions

hal-00842645 , version 1 (09-07-2013)

Identifiants

Citer

S. Miquel, R. Martín, O. Rossi, Lg Bermúdez-Humarán, Jm Chatel, et al.. Faecalibacterium prausnitzii and human intestinal health.. Current Opinion in Microbiology, 2013, 16 (3), pp.255-261. ⟨10.1016/j.mib.2013.06.003⟩. ⟨hal-00842645⟩
125 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More