Editorial: Plasticity of GABAergic synapses - Université Pierre et Marie Curie
Article Dans Une Revue Frontiers in Cellular Neuroscience Année : 2015

Editorial: Plasticity of GABAergic synapses

Résumé

For long time, plasticity of brain circuits has been hypothesized to mainly rely on the flexibility of glutamatergic excitatory synapses, whereas inhibitory synapses have been assumed to be relatively invariant. Based on this view, inhibition should be exclusively modulated by the differential glutamatergic-driven activation of a highly diverse population of inhibitory interneurons displaying specific temporal dynamics and selective innervation patterns. However, it has been demonstrated that inhibitory synapses undergo several forms of plasticity, thus providing an additional source of versatility to the regulation of the neuronal network and the emergence of complex brain states.
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hal-01215424 , version 1 (14-10-2015)

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Andrea Barberis, Alberto Bacci. Editorial: Plasticity of GABAergic synapses. Frontiers in Cellular Neuroscience, 2015, 9, pp.262. ⟨10.3389/fncel.2015.00262⟩. ⟨hal-01215424⟩
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