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Communication Dans Un Congrès Année : 2014

Double emulsion generation and separation by microfluidic consecutive flow focusing

Résumé

This article describes the first developments of a microfluidic circuit for the continuous generation of monodisperse polymersomes. The generation of these vesicles is made in a consecutive flow focusing cross-junctions structure from non miscible fluids. The device allows generating a stream of polymersomes in two steps. The breaking of a focused water flow creates first water droplets in a solution of diblock polymer and then the double emulsion is generated at the second constriction. This paper will describe microflabrication of the device and a study of the dynamics of droplets formation by high frame rate videomicroscopy. The work has been done on liposome in first steps and them with Pb-b-PEO block polymer in a second time. Finally the paper will decribe the addition of a separation structure for sorting generated vesicles by their size.
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Dates et versions

hal-02091447 , version 1 (05-04-2019)

Identifiants

Citer

Benoît Charlot, N. Sanchez, P. Roux, S. Teixeira. Double emulsion generation and separation by microfluidic consecutive flow focusing. 2014 Symposium on Design, Test, Integration and Packaging of MEMS/MOEMS (DTIP), Apr 2014, Cannes, France. pp.1-5, ⟨10.1109/DTIP.2014.7056673⟩. ⟨hal-02091447⟩
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