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Article Dans Une Revue Clinical Oral Investigations Année : 2014

Randomization in clinical trials: stratification or minimization? The HERMES free simulation software

Résumé

Operative clinical trials are often small and open-label. Randomization is therefore very important. Stratification and minimization are two randomization options in such trials. The first aim of this study was to compare stratification and minimization in terms of predictability and balance in order to help investigators choose the most appropriate allocation method. Our second aim was to evaluate the influence of various parameters on the performance of these techniques.

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Matériaux
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Dates et versions

hal-04088042 , version 1 (03-05-2023)

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Hélène Fron Chabouis, Francis Chabouis, Florence Gillaizeau, Pierre Durieux, Gilles Chatellier, et al.. Randomization in clinical trials: stratification or minimization? The HERMES free simulation software. Clinical Oral Investigations, 2014, 18 (1), pp.25-34. ⟨10.1007/s00784-013-0949-8⟩. ⟨hal-04088042⟩
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