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Article Dans Une Revue BMC Medical Research Methodology Année : 2014

Comparison of intervention effects in split-mouth and parallel-arm randomized controlled trials: a meta-epidemiological study

Résumé

Split-mouth randomized controlled trials (RCTs) are popular in oral health research. Meta-analyses frequently include trials of both split-mouth and parallel-arm designs to derive combined intervention effects. However, carry-over effects may induce bias in split- mouth RCTs. We aimed to assess whether intervention effect estimates differ between split- mouth and parallel-arm RCTs investigating the same questions.

Domaines

Matériaux

Dates et versions

hal-04090439 , version 1 (05-05-2023)

Identifiants

Citer

Violaine Smaïl-Faugeron, Hélène Fron Chabouis, Frédéric Courson, Pierre Durieux. Comparison of intervention effects in split-mouth and parallel-arm randomized controlled trials: a meta-epidemiological study. BMC Medical Research Methodology, 2014, 14 (1), pp.64. ⟨10.1186/1471-2288-14-64⟩. ⟨hal-04090439⟩
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